Category Archives: Health

FuseBio Presents New Data at AACR

Woburn, MA, April 10, 2024 — Fuse Biotherapeutics, Inc., a biotechnology company developing functionally-selective cytokines for cancer and autoimmune disease, today announced the presentation of new data with respect to their lead asset PD1-F18, at the American Association for Cancer Research (AACR) Annual Meeting being held on April 5-10, 2024, in San Diego, CA. The Fuse Biotherapeutics team will present data on April 9, 2024 that strongly supports the use of PD1-F18 as a highly differentiated PD-1 targeted IL-18 with first and best in class potent single agent antitumor activity.

FuseBio has leveraged its immuno-oncology and protein engineering capabilities to functionally optimize IL-18 (F-18), creating an IL-18 binding protein-resistant molecule with 1 million percent reduced activity in circulation while retaining nearly full affinity for the IL-18 receptor complex when targeted to an immune cell of interest. F-18 was fused onto a PD-1 inhibitor to create a first-in-class PD1-F18 immunocytokine designed for full PD-1 checkpoint blockade while safely delivering IL-18.

“A tremendous amount of effort was made to design a therapeutic to overcome resistance to PD-1 inhibitors such as Keytruda,” said Brian Rabinovich, Ph.D, Chief Scientific Officer of Fuse Biotherapeutics. “Since the immune cells that remain functional and kill tumors in response to PD-1 inhibitors preferentially express the receptor complex for IL-18, the safe and selective delivery of F18 to these cells not only augments their anti-tumor capabilities but also preserves their capacity to respond to a the drug class that placed immunotherapy firmly on the cancer treatment map.” Jeff Takimoto, Ph.D, the Chief Executive Officer of Fuse Biotherapeutics continued, “That we are able to abolish aggressive and PD-1 inhibitor resistant tumors in animal models without side effects is an incredible achievement for our team. We are excited to embark on moving PD1-F18 to the clinic and view our finding as providing much needed hope for the more than 80% of cancer patients that are either resistant or become resistant to PD-1 inhibitors.”

Enhanced rock weathering results in higher crop yields and improved crop health

Enhanced rock weathering – a nature-based carbon dioxide removal process that accelerates natural weathering – results in significantly higher first-year crop yields, improved soil pH, and higher nutrient uptake, according to a new scientific paper, released in PLOS ONE today.

Enhanced rock weathering (ERW) involves spreading finely crushed silicate rock such as basalt on agricultural land. It is a scalable and permanent climate technology with the potential to sequester gigatonnes of carbon dioxide from the atmosphere. Co-authored by scientists at UNDO, a leading enhanced rock weathering project developer, and Newcastle University, the peer-reviewed publication is the latest enhanced rock weathering (ERW) study assessing the impact on crops in a temperate climate.

Dr XinRan Liu, Head of Science and Research at UNDO and co-author of the paper, commented: “Nutrient limitations in agricultural soils are a major concern for farmers about sustaining and increasing crop yields. This latest study highlights how the spreading of basalt rock on farmland can lead to higher crop yields and can be effective in a temperate climate. This research demonstrates the potential for enhanced rock weathering to contribute to improved farmer livelihoods and food production, whilst also removing CO2 from the atmosphere.”

The results from the ongoing trial’s first year demonstrate that the crop yield was on average 15% higher (9.3% and 20.5% between plowed and direct drill amended plots respectively) across two different cultivation techniques.

The trial results also showed a stabilizing effect on the soil pH, with the soil pH being on average 0.2 and 0.29 pH units higher in the basalt-amended plots, compared to the control plots. This change is a result of alkaline products generated as the rock minerals dissolve. The effect of silicate mineral dissolution on the soil pH could represent an attractive agronomic benefit for farmers as an elevated soil pH allows crops to access more nutrients in the soil.

Basalt rock is rich in minerals that slowly release nutrients during dissolution. These nutrients act as a natural soil amendment and are essential for plant growth. The study found higher nutrient concentrations in the crops grown in the basalt-amended soil, including tissue calcium, grain, and tissue potassium, suggesting that ERW can boost nutrient availability for plants and, as a result, may improve crop yield.

Taking account of the unusually dry growing season conditions in 2022, these findings indicate that basalt amendment could enhance productivity and crop yields, contributing to more sustainable and resilient food production systems in the face of future changes in growing season weather as a result of global warming.

Professor David Manning, Professor of Soil Science, Newcastle University, and co-author of the paper, commented: “The results of this trial give further scientific credibility for enhanced rock weathering and greatly improve its value proposition to farmers. Newcastle University is pleased to partner with UNDO. Our joint research into the co-benefits for farmers of basalt amendment is helping to pave the way for the widespread adoption of enhanced rock weathering in the agricultural community.”

The trial results also show no additional toxic elements taken up by crops in the plots where basalt had been spread. There was no negative impact on the natural environment in this trial, which indicates the food produced from it is safe for consumption. UNDO’s basalt has been approved for use in organic farming systems by respected certification bodies such as the Soil Association.

Yit Arn Teh, Professor of Soil Science, Newcastle University, said: “Independent bodies, such as the IPCC and UK Committee for Climate Change, have repeatedly highlighted the urgent need for climate action in the agriculture and land use sector to counter the effects of dangerous climate change. At the same time, the agricultural sector is under increasing pressure to meet key sustainability and environmental targets, against a backdrop of rising farm operating costs, driven by the cost of living crisis.

“Use of enhanced rock weathering to remove carbon dioxide and naturally enhance soil health represents a potential win-win for farmers and climate as this technology is able to capture carbon dioxide while simultaneously supplying some of the key nutrients that crops require for successful growth. By using locally-sourced rocks, rather than inputs (e.g. fertilizers) obtained from overseas, supply chains are also shortened, further reducing the overall carbon footprint of food production.

“Crucially, enhanced rock weathering is a technology that can be readily adopted by the agricultural sector because it does not require farmers to invest in new equipment, technology or training, but simply utilizes the existing equipment and infrastructure for spreading fertilizer or other soil amendments.”

The authors of the paper hope that the agronomic co-benefits of enhanced rock weathering will further incentivize farmers across the UK and worldwide to take advantage of this nature-based carbon removal solution.

Sakra World Hospital Successfully Performs 100 Robotic GI Surgeries, Enhances Patient Outcomes

Bengaluru 9th April 2024: Sakra World Hospital, a pioneering healthcare facility in India funded entirely by foreign direct investment (FDI), has completed 100 robotic gastrointestinal (GI) surgeries. In the medical field, robotic-assisted surgical procedures are steadily on the rise. The increasing acceptance of robotic surgeries can be attributed to their accuracy, minimally invasive techniques, and capacity to improve surgical outcomes. With a group of skilled surgeons and cutting-edge facilities, Sakra World Hospital has become a pioneer in leveraging this technology to help patients suffering from gastrointestinal surgical issues.

Robotic-assisted surgery enables the performance of intricate procedures across a wide spectrum, including colorectal cancers, and benign and malignant conditions of the liver, biliary system, and pancreas, apart from complex hernia repairs, gallbladder removals, and abdominal wall reconstruction. With a focus on less trauma and greater precision in these surgical interventions, Sakra tremendously benefits patients specializing in upper gastrointestinal surgeries, such as giant hiatal hernias, gastroesophageal reflux disease (GERD), Heller’s myotomy, and even uncommon conditions like median arcuate ligament syndrome.

“We take immense pride in reaching a significant milestone in robotic GI surgeries, underscoring the skill and commitment of our proficient surgical team,” lauded Lovekesh Phasu, Chief Operating Officer, Sakra World Hospital, Bengaluru, adding, “At Sakra, we’re committed to setting high standards and achieving them, to benefit our patients and provide quality healthcare for all.”

The application of robot-assisted technologies has greatly improved surgical capabilities in GI surgeries. These systems are operated directly by surgeons, in contrast to autonomous systems, which enable careful dissection around target organs. Although laparoscopic surgery provides benefits such as accurate dissection under high-resolution imaging and minimally invasive procedures, it has limitations due to the limited dexterity of the instruments. These limitations are overcome by the existing robotic system’s articulated instruments, vibration filtering, and motion scaling functions. These capabilities allow surgeons to perform more versatile surgeries than they could with standard laparoscopic equipment.

Moreover, the robotic system’s instruments with wrist-like movements and dexterity assures delicate tissue handling and precision surgery with minimal bleeding. This capability, coupled with three-dimensional magnified, enhanced imaging, provides a platform wherein complex procedures in critical places and organs can be safely performed. Through these innovations, robotics surgery in the gastrointestinal realm continues to push boundaries, enhancing surgical precision and expanding treatment options for patients.

Robotic GI surgery has emerged as a reassuring alternative to traditional methods, dispelling common fears. The robotic system not only provides surgeons with better visualization and precision, but the patient also benefits from smaller incisions, less blood loss, quicker recovery, and reduced post-operative pain.

“The completion of 100 robotic GI surgeries at Sakra World Hospital not only marks a numerical achievement but also serves as evidence of the hospital’s steadfast dedication to delivering top-notch care to its patients,” remarked Dr Sadiq Saleem Sikora, Director of Gastrointestinal Surgery and Liver Transplantation at Sakra World Hospital, Bengaluru.

Lorrinda Gray-Davis to Speak at TRIO’s Remember & Rejoice Event

Oklahoma City, OK, April 09, 2024 — Transplant Recipients International Organization (TRIO) is thrilled to announce that Lorrinda Gray-Davis, a distinguished advocate for organ donation and transplantation, will be a guest speaker at the upcoming “Remember & Rejoice” ecumenical service. This event, dedicated to honoring organ, eye, and tissue donor families and celebrating transplant recipients, will take place on Saturday, April 6, 2024, at the historic St. Patrick’s Cathedral on 5th Avenue in New York City.

Lorrinda Gray-Davis is widely recognized for her unwavering commitment to promoting awareness about organ donation and advocating for policies that support transplant recipients and their families. As a transplant recipient herself, Gray-Davis brings a deeply personal perspective to her advocacy work, inspiring others with her resilience, courage, and passion for making a difference in the lives of those affected by organ failure.

“Remember & Rejoice” stands as the single largest gathering of donor families and transplant recipients in the country, providing a sacred space for reflection, remembrance, and rejoicing. Through heartfelt testimonials, musical performances, and moments of unity, attendees will pay tribute to the selfless donors and their families who have forever changed the lives of others through the gift of life.

As a guest speaker, Lorrinda Gray-Davis will share her personal journey of hope, resilience, and gratitude, highlighting the profound impact of organ donation on individuals, families, and communities. Her presence underscores the importance of raising awareness about the critical need for organ donors and supporting initiatives that promote transplantation as a life-saving treatment option.

“Remember & Rejoice” is open to all members of the community who wish to honor the legacy of organ donors, celebrate the resilience of transplant recipients, and support the cause of transplantation. Together, we can unite in solidarity to inspire others to register as organ donors and help save lives.

Introducing Crane Wellness

Santa Ana, CA, April 09, 2024 –Fine USA Trading, a pioneer in the beauty and wellness industry, is proud to unveil its latest venture, Crane Wellness. Rooted in a family legacy of excellence dating back to 1974, Crane Wellness represents a fusion of cutting-edge science, premium ingredients, and Japanese ancient wisdom and traditions.

Crafted at our state-of-the-art facilities in Osaka, Japan, Crane Wellness embodies a commitment to holistic well-being, harnessing the power of nature and technology to redefine beauty and wellness standards. Our meticulously curated range of products is designed to nourish both body and soul, empowering individuals to embrace their full potential and thrive better, longer.

“We are thrilled to introduce Crane Wellness to the world,” said Hiroo Kato, CEO at Fine USA Trading. “With our decades-long expertise and dedication to quality, we aim to inspire a new era of self-care, where beauty radiates from within and longevity and wellness is a way of life. By sharing our ancient Japanese secrets with the world, we hope to encourage holistic habits for longevity and thriving to 100.”

At Crane Wellness, they believe in the transformative power of nature’s finest ingredients, combined with the latest advancements in scientific research. Each product is thoughtfully formulated to deliver tangible results, whether it’s promoting radiant and youthful skin, supporting overall vitality, or enhancing daily life.

By using traditional, time tested ingredients to create uniquely formulated non-gmo, gluten free products. The Nattokinase Blend for blood and heart health, Tone & Glow which is a Coix Seed Extract Powder for beauty-from-within, Pure Oceanic Root Iodine – a kelp fronds extract sourced from regenerative ocean farms off the northern coast of Japan, to name a few. Crane Wellness shows their dedication to sustainability, ethical sourcing, and recyclable packaging, making it a responsible choice for a thriving individual and a thriving planet.

As they embark on this exciting journey, Crane Wellness invites you to join them in embracing a lifestyle that celebrates beauty, wellness, and the harmony between mind, body, and spirit.

PocketRN Brings No Cost Virtual Nurse for Life

Washington, DC, April 09, 2024 — PocketRN, a leading provider of virtual nursing care, today announced its acceptance as a participant in the Guiding an Improved Dementia Experience (GUIDE) Model by the Centers for Medicare & Medicaid Services (CMS) Innovation Center. The CMS GUIDE Model is a groundbreaking initiative designed to enhance the quality of life for individuals with dementia and alleviate the burden on their caregivers.

As a GUIDE participant, PocketRN’s innovative “Virtual Nurse for Life” approach will allow dementia patients and caregivers to be specialty-matched to nurses, who become trusted companions that establish a profound and lifelong relationship with patients and families. PocketRN nurses also encourage openness to better understand individualized challenges, and serve as continuous sources of education, coaching, monitoring, emotional support, and a 24/7 lifeline. Under the GUIDE Model, PocketRN will be available at no cost to eligible members, with $0 copays.

The anticipated outcomes of the GUIDE Model include increased caregiver empowerment and a reduction in Medicare and Medicaid expenditures–primarily achieved by preventing or delaying long-term nursing home stays. Additionally, the program aims to bring about a secondary reduction in hospital, emergency department, and post-acute care utilization. These outcomes closely align with the work that PocketRN is already doing and its mission to close the gap between home and healthcare.

“We couldn’t be more thrilled to bring our revolutionary nurse-led care model to the millions of dementia patients and families who need it most,” said CEO Jenna Morgenstern-Gaines. “With PocketRN, patients and families get unwavering support from a ‘virtual nurse for life’ as they navigate the complexities of managing dementia at NO cost to them. Nurses are hands-down the best clinicians to be the ‘glue’ to dementia patients and families throughout their journey–they’ve been doing so forever, and it’s high-time their work is valued by our system.”

PocketRN’s Head of Innovation, Samuel Thomas, also expressed, “Ultimately, this is a way to provide more equitable, accessible care to a vast population of dementia patients and families that we’re already serving and haven’t been able to serve yet because of existing reimbursement frameworks. It’s an incredible opportunity to bring about positive change and enhance the lives of those who truly need more support, in the most cost-effective and highest-quality way.”

PocketRN will utilize its national network of expert nurses to dramatically expand access for dementia patients and families who otherwise may go without care. Its participation in the GUIDE Model will span eight years, with a one-year pre-implementation period for program development, community engagement, and infrastructure scaling before rolling out with a cohort of initial partners.

Amidst The Accelerating Summer Temperature Be Precautious Towards Your General Health & Eyes

The General Elections are around the corner and campaigning has started in full swing. Since it is the scorching summer, it is important to take care of one’s overall health for both the Candidate and the supporters. The scorching heat makes our body go through several complications that unknowingly damage our internal organs, skin, and eyes. To prevent serious medical complications, one must focus on adopting certain precautionary measures that will help one to stay fit and healthy.

Dr Payel Kumar Roy, Chief Dietician & Critical Care Nutritionist, Techno India DAMA Hospital & Healthcare Medical Centre throws light on crucial dietary suggestions for maintaining a healthy body while doing election promotions.

One needs to consume light and easy foods as their daily diet. Such foods and drinks protect against dehydration and help maintain optimal levels of energy.

Eat a lot of fresh fruits, salads, and lightly spiced foods as the fruits and veggies are easy to digest. They bear high water content and help in hydration. Avoid fried and junk foods as they take time to digest and require a lot of water. Spicy foods can also increase body heat. Summers can be incredibly exhausting and can leave one feeling drained out. Nothing is better than refreshing oneself with quick and tasty drinks. Fruit juices like Wonder watermelon, Lemon punch, Cool cucumber, and Masala Jeera. All these may vary in nutritional value but most of them have a variety of health benefits. They contain various antioxidants which help to reduce the risk of certain health issues and vitamins that help the body to function well.

Apart from this, below are additional steps that can be undertaken as safety measures to combat the adverse impact of the heat wave.

a. Clean your face with cold water but not constantly. After washing, rub ice on the face.

b. Apply the sunscreen lotion whenever you are about to get exposed in the scorching heat. This will help in avoiding dark shades on the skin and will also prevent developing allergies from the sweat and heat.

c. Must include more Vitamin C and Calcium in the diet.

d. Include more water or fluid to keep the body well hydrated.

e. Light oils such as jojoba oil, lavender oil, Rosehip oil and grape seed oil can be used since these oils do not have a heavy consistency. They do not clog pores, instead, they hydrate your skin.

Dr Abhishek Kayal from Disha Eye Hospitals – Kolkata further adds some valuable suggestions regarding the eye-related problems that an individual can encounter due to rising temperatures outside with the remedies related to this.

While campaigning for the Lok Sabha Election 2024 in the summer season most of the people are affected with dehydration, heat stroke, and skin darkening. Common eye problems that one faces when the temperatures rise are allergies, conjunctivitis, and style. Protection and proper eye hygiene can help one keep away from excessive heat-driven eye problems. People who suffer from allergic diseases like asthma, eczema, etc are more prone to eye allergy. Common allergens that cause eye allergies are diesel exhaust, cigarette smoke, and perfumes.

Allergens cause our eye to release histamine that in turn makes your eye swell, become watery, and turn red. The symptoms of eye allergies are Swollen eyes, Red eyes, Puffy eyes, Itchy eyes or a burning sensation, Eyes watering excessively, and Stringy eye discharge Vessels in the clear tissue covering the white portion of the eye could be dilated.

In such circumstances, the patients are advised to rinse their eyes repeatedly with either cold or warm water, and then to wipe it gently with a soft tissue. Rose water is another natural remedy that has been used through the ages. Use 3 to 4 drops of rose water in both your eyes. Shut your eyes for around 5 minutes so that its full effects can take place. Avoid wearing contact lenses and in case you wear them you are advised to stop wearing them until treatment is complete. Disinfect hard lenses overnight before you reuse them. If home remedies do not work, your doctor can help you by prescribing suitable medication that will help you cure the infection.

Dr D. Nageshwar Reddy inaugurates the Gastroenterology Department and Deluxe Rooms at Mahavir Hospitals

Hyderabad,8th April 2024 …. The Gastroenterology Department and Deluxe Rooms opened at Mahavir Hospital & Research Center at Mahavir Hospital at Masabtank, Hyderabad

Dr. D. Nageshwar Reddy, Chairman & Founder, Asian Institute of Gastroenterology inaugurated the same.

Speaking on the occasion, Dr D. Nageshwar Reddy, a well-known doctor in Gastroenterology across India said Mahavir Hospital has been doing a lot of yeoman service for many years

The gastroenterologist specialization looks at disorders and diseases that affect the digestive system — including the gastrointestinal tract (esophagus, stomach, small intestine, large intestine, rectum and anus), as well as the pancreas, liver, bile ducts and gallbladder etc, is most important. The diseases related to this are on the rise and facilities like this are most welcome, Dr D. Nageshwar Reddy said.

Mahavir Hospital with a reputation of over four decades of serving the poor and needy regardless of religion, caste & creed, is now committed to upgrading all departments with the latest equipment for better health care of the patients, the hospital release said.

The Gastroenterology wing was donated by Smt Chandrakaladevi Kantilal Nahar and his Family. Gastroenterology Department Equipment was supported by hubergroup.

The deluxe ward donors are Sri Hanumanmal Suman Nakhat & Family; Sri Prakash Kamdar & Family, Shri Satish Dr. Asha Khivasara & Family; Sri Mahadeerachand Vijayalaxmi Chopra & Family; Sri Ghewarchand Vinayakiya & Family, Sri Lalith Bhansali & Family, Sri Rupender Sunil Anvil Vishal Ostwal & Family; JITO Ladies Wing; Sri Anil Saraswati Devi Bhojani & Family; Sri Gauthamchand Kamladevi Gugalia & Family and Sri Sthankwasi Chandanbala Mahila Mandal.

Dr. Rupendra Prasad, MD, Gastroenterology Department Head, Mahendra Ranka, Chairman; Sushil Kapadia, Vice Chairman, Sushil Sancheti Trustee Treasurer, Sushil Pahade, Managing Trustee; standing committee members Dr Asha Khivsara, Dr, Ghisulal Jain, Nitin K Shah, Paresh Shah, Rajesh Parak, Rajesh Pokerna, Ramesh Kundalia, Sheel Kumar Jain, Vijay Surana, Vimal Ranka, Yogesh Jain and all trustees participated in the inaugural function.

Revolutionizing Healthcare Insights

Dubai, United Arab Emirates, April 06, 2024 — In an era where data-driven decisions are paramount, the healthcare industry stands at the forefront of leveraging insights to enhance patient care, optimize operations, and drive innovation. Today, they proudly announce that 42 market research is successfully operating in more than 60 countries around the world interviewing physicians, dentists, pharmacists, opticians, dietitians and other healthcare-related professionals concerning their experiences and opinions towards any health-related subject; all 100% online.

As pioneers in online healthcare market research, 42 market research brings together decades of experience in advising you on who you should interview; recommended sample sizes; plus the location and demographic distributions of the study respondents to secure the most statistically viable results for your projects.

“Obtaining accurate real-world results as quickly as possible is key for the pharmaceutical companies to understand and react to what is happening within the marketplace,” explains Stuart Crocker, Managing Director of 42 market research. He also added that, “42 market research is able to deliver that information by utilising our extensive network of respondents and experience that we have developed in the 22 years we have been operating.”

Inspire Weight Loss Davie Reflects on Wellness During Solar Eclipse

Davie, FL, April 06, 2024 — With the upcoming solar eclipse captivating minds worldwide, Inspire Weight Loss Davie takes a moment to ponder the significance of wellness amidst this celestial spectacle. Focused on holistic health, the center encourages individuals to view this event as an opportunity for personal reflection and rejuvenation.

As the moon temporarily veils the sun, casting a shadow across the Earth, it prompts contemplation on the balance between light and darkness, symbolizing transitions and renewal. Inspire Weight Loss Davie invites individuals to pause and consider their own balance of health and well-being during this cosmic alignment.

Echoing the sentiment of cosmic harmony, Inspire Weight Loss Davie advocates for individuals to embark on their own journey of transformation towards wellness. Through personalized programs and unwavering support, the center empowers individuals to achieve sustainable weight loss, vitality, and overall well-being.

“As we marvel at the solar eclipse, let’s also take a moment to reflect on our own paths to wellness,” says Martha Savloff MCHC, Founder of Inspire Weight Loss Co-Founder of Inspire Franchise. “We believe every individual has the potential to shine and embrace their best selves. Let this celestial event inspire positive change and a renewed commitment to health.”

Inspire Weight Loss Davie encourages individuals to embrace the solar eclipse as an opportunity for self-reflection and renewed dedication to holistic health. By prioritizing well-being, individuals can harness the energy of this cosmic event to embark on a journey towards a healthier, happier life.