18, Jul 2026
PV Sindhu Reaches Japan Open Final After Beating Chen Yufei
Tokyo, July 18: Indian badminton star PV Sindhu has entered the Japan Open 2026 final after defeating Olympic champion Chen Yufei in a memorable clash.
Sindhu displayed determination, experience, and strong gameplay to overcome her Chinese opponent, marking her return to a major final after two years.
The victory has renewed hopes among Indian badminton fans as Sindhu aims to add another prestigious title to her career. Her impressive performance continues to highlight her fighting spirit and lasting impact on the sport.
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- By Neel Achary
18, Jul 2026
Immune Cells Use Previously Unknown Pathway to Eliminate AML
Houston, July 18: Researchers at The University of Texas MD Anderson Cancer Center have discovered a new way in which T cells attack acute myeloid leukemia (AML) cells, which may help explain why AML is particularly sensitive to immune-based treatments and could guide the development of future cancer immunotherapies.
The study, published in Proceedings of the National Academy of Sciences (PNAS), was led by Cassian Yee, M.D., professor of Melanoma Medical Oncology, and Kapil Saxena, M.D., former member of the Yee laboratory. The findings reveal that leukemia cells, which lack the molecular machinery normally required for T cell recognition, use a different pathway that depends on the CD64 protein and an intact T cell receptor (TCR).
“By chasing a simple, unexplained observation, we challenged a basic assumption about how T cells can recognize and kill tumor cells,” Yee said. “The freedom to explore things that aren’t conventional is what drives innovation, and this contrarian finding is an example of that, with broad implications for overcoming immune resistance in leukemia and possibly other cancers.”
What makes AML difficult to treat?
AML is an aggressive blood cancer that begins in the bone marrow and can progress rapidly. Although targeted therapies and stem cell transplantation have improved outcomes for some patients, many individuals experience relapses or develop treatment resistance.
One challenge is that cancer cells can evade immune attack by reducing or losing immune signaling molecules, a set of proteins known as the major histocompatibility complex (MHC) which normally helps T cells identify their targets.
What did the researchers discover about the way T cells eliminate AML cells?
T cells typically recognize cancer through their TCR, which binds to specific cancer-related peptides displayed on MHC molecules. The researchers expected that removing MHC from AML cells would prevent T cell attack.
Instead, activated T cells were somehow still able to efficiently eliminate the AML cells. This pattern was seen in multiple AML cell lines and in primary samples from patients with AML, including those with high-risk mutations and relapsed disease.
Why was this new pathway surprising?
The researchers suspected that this mechanism might be driven by pathways associated with natural killer (NK) cells, which are not dependent on MHC molecules. However, disrupting several known NK cell pathways did not eliminate the effect.
Since MHC molecules did not seem to be required, the researchers hypothesized that the TCRs also were unnecessary for this alternative killing pathway. Surprisingly, the T cells lost their ability to destroy the leukemia cells when the researchers removed TCRs.
This means that T cells can destroy AML cells through a different, unknown pathway that is MHC-independent but TCR-dependent. In other words, T cells still require an intact and activated TCR signaling system, but they are not using it in the conventional way scientists have understood for decades.
How did the researchers identify the key drivers in the new pathway?
After testing several known immune pathways, the researchers performed a genome-wide CRISPR screen, repeatedly exposing genetically modified AML cells to T cells to search for genes that allowed the leukemia cells to survive.
This approach highlighted CD64, a receptor commonly expressed on early myeloid cells, as well as genes involved in interferon-gamma signaling. Removing CD64 made AML cells resistant to T cells, while adding CD64 into normally resistant AML cells made them more susceptible.
What do these findings mean and what are the next steps?
Overall, these findings revealed a previously unknown mechanism of T cell-mediated killing that depends on CD64 and activated TCR, but not on traditional MHC recognition. The results suggest that T cells have an additional way to attack leukemia, which may help explain why AML may be especially sensitive to stem cell transplantation, which is one form of immune-based therapy.
The researchers continue to investigate exactly how CD64 and the TCR signaling machinery interact, with future studies exploring how these mechanisms might be leveraged to improve T cell therapies for AML and possibly other cancer types.
18, Jul 2026
Gold, Silver Outlook Turns Cautious Amid Global Market Uncertainty
Mumbai, July 18: Gold prices on the Multi Commodity Exchange (MCX) may see further movement toward the ₹1.39 lakh support level as global uncertainty continues to influence precious metal markets, according to analysts.
Market experts said changing global economic conditions, currency trends, and investor sentiment are playing a key role in shaping gold and silver prices. While gold continues to remain a preferred investment option during uncertain times, short-term fluctuations are expected.
Silver prices have also come under pressure, with analysts maintaining a cautious outlook due to weak global cues and market volatility.
Investors are closely monitoring key price levels and international developments to assess the future direction of precious metals. Despite near-term challenges, gold and silver continue to remain important assets for investors seeking stability during uncertain market conditions.
18, Jul 2026
PM-AJAY Drives Inclusive Growth, Brings Development Benefits to Millions Across India
New Delhi, July 18: The Pradhan Mantri Anusuchit Jaati Abhyuday Yojana (PM-AJAY) has emerged as a key initiative in promoting inclusive development, benefiting over 47.5 lakh people and supporting transformation efforts across 16,759 villages, according to government figures.
The scheme has been designed to improve socio-economic conditions among Scheduled Caste communities by supporting infrastructure development, livelihood opportunities, and access to essential resources. Through targeted interventions, PM-AJAY aims to strengthen communities and create pathways for sustainable growth.
Government data highlights the wide reach of the programme, with thousands of villages benefiting from development initiatives aimed at improving quality of life and promoting greater economic participation.
The initiative reflects the government’s focus on inclusive growth and empowering communities through improved opportunities and grassroots-level development. PM-AJAY continues to play an important role in supporting social advancement and building a more equitable future.
18, Jul 2026
Mexico Coast Rocked by Strong Quake, President Confirms No Damage
Mexico, July 18: A powerful earthquake measuring 7.4 magnitude struck off the southern coast of Mexico on Friday, according to preliminary data from the United States Geological Survey (USGS).
The strong tremor was felt across parts of the region, prompting authorities to assess the situation and monitor possible impacts. Mexico’s President said that no major damage had been reported following the earthquake.
Emergency agencies remained on alert and continued carrying out assessments to ensure public safety. Officials advised residents to remain cautious and follow safety guidelines as aftershocks may occur following a major seismic event.
The earthquake has once again highlighted the importance of preparedness and rapid response measures in one of the world’s most earthquake-prone regions.
18, Jul 2026
The Flavours and Folklore of Bonalu Come Alive at The Bheemili Resort
Bheemili, July 18: This Bonalu season, experience the rich flavours and vibrant traditions of Telangana at The Bheemili Resort Managed by Accor as it presents Bonalu Bhojanam, a specially curated 10-day festive culinary celebration. Available for lunch, the festival invites guests to savour the essence of one of Telangana’s most cherished cultural celebrations through an authentic regional feast.
Inspired by Bonalu, the iconic festival dedicated to Goddess Mahakali, the culinary experience pays tribute to a tradition that brings communities together through devotion, music, dance, and generous festive meals. At Bonalu Bhojanam, every dish reflects the warmth of home and the richness of local ingredients, creating an immersive celebration of Telangana’s culinary heritage.
The specially crafted menu showcases a vibrant selection of regional favourites, including Sarva Pindi, Sakinalu, Garelu, Pachi Pulusu, Natu Kodi Pulusu, Jonna Rotte, Gongura specialties, and an array of traditional festive desserts. Prepared using locally sourced ingredients and time-honoured cooking techniques, each dish celebrates the authentic flavours that define Telangana’s festive cuisine.
Complementing the culinary journey, The Square will be adorned with vibrant Bonalu-inspired décor, recreating the festive charm of a traditional Telangana celebration. The inviting ambience, combined with warm hospitality and soulful regional flavours, promises an unforgettable dining experience for families, friends, food enthusiasts and cultural explorers alike.
Whether you are reliving the nostalgic flavours of home or discovering Telangana’s festive cuisine for the first time, Bonalu Bhojanam at The Bheemili Resort offers a heartfelt celebration of tradition, and exceptional dining experience
Event Details
Venue: The Square, The Bheemili Resort Managed by Accor
Dates: 17 – 25 July 2026
Time: 12:30 PM – 3:30 PM
18, Jul 2026
A Cricket Legend Bids Farewell: Sir Garry Sobers Dies
New Delhi, July 18: The cricketing world is mourning the passing of Sir Garfield Sobers, widely regarded as one of the greatest all-rounders in the history of the sport. He died at the age of 89, leaving behind a remarkable legacy that inspired generations of cricketers across the globe.
Tributes have poured in from cricket boards, former players, and sporting personalities who remembered Sir Garry Sobers for his extraordinary talent, elegance, and unmatched contribution to the game. The Board of Control for Cricket in India (BCCI), West Indies Cricket, and several former Indian cricketers expressed their condolences and celebrated his incredible journey.
Former India captain Sunil Gavaskar described Sobers as one of cricket’s brightest stars, highlighting his impact both on and off the field. Other cricketing greats, including Sachin Tendulkar, Virat Kohli, Harbhajan Singh, Ishant Sharma, and Ajinkya Rahane, also paid heartfelt tributes, remembering him as a true icon of the sport.
International cricket bodies, including the International Cricket Council (ICC), also expressed their grief, acknowledging Sobers’ immense influence and his role in shaping the history of cricket. His skill with the bat, ball, and in the field made him a complete cricketer and a benchmark for future generations.
Sir Garry Sobers’ illustrious career, marked by record-breaking performances and moments of brilliance, earned him admiration worldwide. His legacy will continue to live on through the countless players and fans he inspired throughout his extraordinary life in cricket.
18, Jul 2026
Skyroot Aerospace’s Vikram-1 Mission Marks a New Milestone in India’s Private Space Journey
New Delhi, July 18: India’s space sector is set to witness another landmark moment as Skyroot Aerospace prepares for the launch of its Vikram-1 rocket, with Prime Minister Narendra Modi extending his best wishes to the team and highlighting the mission’s importance for the country’s space ambitions.
The Vikram-1 launch represents the growing strength of India’s private space ecosystem and showcases the capabilities of homegrown innovation in developing advanced space technologies. The mission reflects the increasing contribution of private companies in expanding India’s presence in the global space sector.
Recognising the efforts of Skyroot Aerospace, the Prime Minister praised the team’s commitment to innovation and entrepreneurship, noting that such initiatives are helping build a stronger and more self-reliant space industry.
The mission is expected to encourage greater participation from startups and private enterprises, creating new opportunities in commercial space activities while inspiring young innovators to explore the possibilities of space technology.
The upcoming launch highlights India’s continued progress in space exploration and its vision of becoming a leading force in the global space economy.
18, Jul 2026
Monsoon Showers to Bring Relief Across Tamil Nadu as Chennai and Western Ghats Prepare for Rainfall
Chennai, July 18: Rainfall activity is expected to increase across Tamil Nadu, with Chennai likely to receive moderate showers and several Western Ghats districts set to experience continued rainfall until July 23.
The upcoming showers are expected to bring relief from warm and humid conditions, while supporting water availability and agricultural activities across the state. The Western Ghats regions are likely to witness more consistent rainfall due to active monsoon conditions.
Authorities have advised residents to stay updated on weather alerts and exercise caution, especially in areas vulnerable to waterlogging and rain-related disruptions. Local administrations are monitoring the situation and taking necessary measures to ensure public safety.
The expected rainfall is part of the ongoing monsoon activity across the region, with weather officials continuing to observe developments and provide updates to the public as needed.
18, Jul 2026
IndiGo to Shift Flight Operations to Guwahati’s Newly Commissioned Integrated Terminal
Guwahati, July 18: IndiGo has announced that it will shift its flight operations to the newly built integrated terminal at Lokpriya Gopinath Bordoloi International Airport in Guwahati, marking a significant milestone in enhancing the travel experience and strengthening aviation infrastructure in Northeast India.
The transition to the modern terminal is expected to provide passengers with improved facilities, streamlined check-in and boarding processes, enhanced baggage handling systems, and greater operational efficiency. Designed to accommodate growing passenger traffic, the new terminal features upgraded infrastructure and advanced technology aimed at delivering a seamless travel experience.
The relocation of IndiGo’s operations reflects the airline’s commitment to supporting the modernization of airport infrastructure while meeting the increasing demand for air travel in the region. The move is also expected to improve flight operations and enhance overall service quality for passengers travelling to and from Guwahati.
The shift to the new terminal underscores the continued expansion of aviation infrastructure in Northeast India and is expected to contribute to improved connectivity, passenger convenience, and regional economic growth.
