Category Archives: News

ten23 Health, West Partner for Synchrony™ S1 Syringe Manufacturing Readiness

ten23 health and West collaborate to ensure manufacturing readiness for West Synchrony™ S1 Prefillable Syringe System filling

Basel, Switzerland. May 4^th, 2026 — ten23 health®, a global contract development and manufacturing organization (CDMO) specializing in sterile fill-finish and advanced drug delivery systems, today announced that it has already successfully tested and ran the newly launched West Synchrony™ S1 prefillable syringe (PFS) system on its manufacturing equipment. The announcement follows West Pharmaceutical Services, Inc.’s global commercial availability of the West Synchrony S1 PFS system, an innovative platform that uniquely integrates the syringe barrel, plunger, and needle shield/tip cap into a fully harmonized, verified system from a single supplier.

 
By evaluating the container system early on its fill-finish lines, ten23 health enables biopharma customers to rapidly adopt the West Synchrony S1 PFS system for clinical and early commercial programs, reducing technical risk and accelerating development timelines.

“Having already implemented and tested the West Synchrony S1 prefillable syringe system on our equipment, we are well positioned to support our partners with operational readiness,” said Hanns-Christian Mahler, Chief Enablement Officer, ten23 health. “Early hands-on experience with new container systems is critical for de-risking development, particularly as combination products and home-based administration continue to grow.”

The West Synchrony S1 PFS system offers a broad portfolio of configurations for biologics and vaccines, including staked needle and Luer lock options, along with high-performance NovaPure® and FluroTec™ film laminated plunger components. ten23 health’s early evaluation focused on manufacturability, compatibility, and process robustness under representative fill-finish conditions.
As drug developers face increasing regulatory and technical complexity, early alignment between container systems and manufacturing processes has become essential. ten23 health’s proactive early adoption and testing approach allows clients to transition seamlessly from development into clinical supply using commercially available, validated delivery platforms and add to ten23’s toolbox for available container and delivery options for its customers.

ten23 health will co-host an event together with West today (May 4^th) at its Basel premises, showcasing the filling of the Synchrony syringes on its pilot filling line.

Dr. Bhargav Mallappa Celebrates Thalapathy Vijay’s Historic Breakthrough

Chennai, May 4, 2026

In the wake of a sweeping electoral victory by actor-turned-politician Joseph Vijay Chandrasekhar, social entrepreneur & National Chairman and Founder of Akhilia Sevak Samaj Council, Dr. Bhargav Mallappa, extended his congratulations, calling the mandate a reflection of “aspiration-led politics and a decisive public shift.”

Vijay’s party, Tamilaga Vettri Kazhagam, has emerged as the dominant force in the 2026 Tamil Nadu Assembly elections, leading in over 100 seats in the 234-member Assembly, marking a significant break from the long-standing DMK-AIADMK duopoly. The results indicate a strong voter endorsement of a new political narrative centred on governance reform and youth engagement.

Reacting to the outcome, Mallappa said the verdict goes beyond a routine change of government. “This is a mandate for accountability and forward-looking leadership. It shows that people are willing to place trust in new ideas when they are backed by credibility and connect,” he noted.

Known for his work at the intersection of social impact and grassroots innovation, Mallappa emphasised the opportunity ahead for inclusive growth. He highlighted that the incoming leadership would need to prioritise employment generation, digital access, and community-driven development to sustain public confidence.

He also underlined the importance of institutional continuity, adding that electoral success must translate into measurable governance outcomes. “The real test begins now, how effectively this mandate is converted into policy action that benefits the last mile,” he said.

The 2026 result is being viewed as a watershed moment in Tamil Nadu politics, with Vijay’s rise signalling the arrival of a new political axis. Stakeholders across sectors, including civil society voices like Mallappa, have expressed cautious optimism about the state’s next phase of governance.

Vijay Hailed as ‘Jana Nayagan’ as TVK Leads; Celebrities Applaud Historic Surge!

Chennai,May 4 (BNP): Actor-turned-politician Vijay is being hailed as ‘Jana Nayagan’ (People’s Leader) as his party, Tamilaga Vettri Kazhagam, takes a commanding lead in the Tamil Nadu Assembly elections, leading in over 100 of the state’s 234 seats as counting trends continue.

The strong electoral showing has triggered a wave of congratulatory messages from across the film industry. Prominent actors including Vikram, Vijay Deverakonda, Nani, Ravi Teja and Kajal Aggarwal took to social media to praise Vijay’s remarkable political debut.

Highlighting the underdog narrative behind Vijay’s rise, Nani lauded the development as a powerful moment in politics. In his message, he noted that Vijay’s journey—from being doubted to gaining widespread public support—resonates strongly with voters and reflects a clear mandate for change in the state.

The outpouring of support from the film fraternity underscores Vijay’s widespread appeal beyond cinema and his growing influence in the political arena. Analysts believe that such endorsements reflect a broader cultural shift, with new-age leadership gaining traction among younger and aspirational voters.

As trends continue to unfold, Vijay’s performance is being seen as a potential turning point in Tamil Nadu’s political landscape, challenging long-standing power structures and redefining electoral dynamics in the state.

Further updates are awaited as counting progresses.

PM Modi to Address BJP Workers as NDA Gains Ground in Assam, West Bengal!

New Delhi, may 4 (BNP): Prime Minister Narendra Modi is set to address party workers at the Bharatiya Janata Party headquarters in the national capital, as the National Democratic Alliance registers a strong surge in the Assembly election trends in Assam and West Bengal.

Early counting trends indicate a significant lead for the Bharatiya Janata Party and its allies, positioning the NDA for a robust performance in both states. The developments have sparked celebrations among party workers, with preparations underway at the BJP headquarters for the Prime Minister’s address.

Sources within the party said Modi is expected to thank voters and party workers for their support, while outlining the alliance’s vision for governance and development in the states.

The surge in Assam and West Bengal is being viewed as a major political gain for the NDA, potentially reshaping the regional political landscape and strengthening the BJP’s footprint in eastern India.

Further updates are awaited as counting progresses and results are officially declared.

End of an Era: CM M.K. Stalin Loses Kolathur Stronghold to TVK Newcomer V.S. Babu!

Chennai,May 4 (BNP): In a landmark political upset, M. K. Stalin, Chief Minister of Tamil Nadu and president of the Dravida Munnetra Kazhagam, has lost his long-held Kolathur seat to first-time candidate V.S. Babu of the Tamilaga Vettri Kazhagam.

The unexpected defeat marks a significant turning point in Tamil Nadu’s political landscape, bringing an end to Stalin’s dominance in Kolathur, a constituency widely regarded as a DMK stronghold for years. The result underscores a shifting voter sentiment and the emergence of new political forces in the state.

V.S. Babu’s victory highlights the rapid rise of TVK, led by actor-turned-politician Vijay, which has made a strong impact in its electoral debut. The outcome is being viewed by political observers as a clear signal of evolving electoral dynamics and growing public appetite for change.

The development is likely to have far-reaching implications for the future of Dravidian politics, potentially reshaping traditional power structures in the state.

Further details are awaited as counting concludes and final results are officially declared.

Centre Pushes Highway Development in Maharashtra, Gadkari Reviews Projects

New Delhi, May 4 (BNP): Union Minister for Road Transport and Highways Nitin Gadkari reviewed a range of ongoing and proposed highway projects in Maharashtra, with a focus on improving connectivity and speeding up infrastructure development.

The meeting looked at plans to upgrade several important road stretches, including widening key routes and developing major corridors that connect different parts of the state and beyond. These projects are expected to ease travel, reduce congestion, and support economic activity in the region.

Among the projects discussed were the expansion of routes such as Nagpur–Bhandara and Taloda–Burhanpur, along with key corridors linking areas like Gadchiroli, Raipur, Vizag, and Nagpur.

The minister also reviewed nine road projects planned under the Build-Operate-Transfer (BOT) model, covering over 500 km of highways. This approach is aimed at bringing in private investment to accelerate construction and improve efficiency.

Officials said the overall goal is to build faster, safer, and more reliable road networks that can support trade, improve mobility, and contribute to the state’s growth.

Helping Your Child Befriend an Autistic Peer

As a parent, you want your child to be inclusive and accepting of the people they encounter—including those with autism spectrum disorder. 

Approximately 95% of children with disabilities enroll in traditional schools. That means your child is likely to meet someone with autism in class or extracurricular activities, whether they realize it or not.

“Given greater awareness of autism and our ability to diagnose children with the condition earlier, more children are being identified as autistic,” says Taryn Liu, DO, MPH, MS, pediatric neurologist and the director of the Neurodevelopmental Disabilities Fellowship at Children’s Hospital Los Angeles. 

“This means most kids will meet or know an autistic child at some point during their school-aged years,” she adds.

Autism involves a wide range of differences that may leave your non-autistic child feeling full of questions or even confused and uncomfortable.

“Sometimes those differences will be obvious, and sometimes they will not,” Dr. Liu says. “But when non-autistic children make friends with someone with autism, it can help them understand that we all have different ways of existing in the world. Parents can help their children navigate those differences and foster meaningful relationships.”

Explaining autism to your kids

Having basic knowledge about autism can go a long way in helping your child understand and interact with an autistic classmate.

Let your child know that autism:

• Describes differences in the way someone communicates or interacts with others
• Enables someone to see and feel the world differently
• Is a difference in how the brain works
• Is not the same for everyone—no two people with autism will communicate or behave in the same way
• Is not a disease or illness; it does not need to be fixed. 

The core feature of autism is social and emotional communication difficulties and can often include behaviors regarding strong interests or environmental sensitivities, Dr. Liu explains. Someone with autism may struggle to understand others’ emotions, facial expressions, and jokes.

“Autistic children may have a hard time initiating conversations or creating new friendships, but that doesn’t mean they’re not just as excited as other kids about making friends,” she adds. “They are often very funny and love to joke around—they just might do it in different ways or even at unexpected times.”

You can help support your child’s friendship with an autistic peer before, during, and after that friendship begins. It’s never too early—or too late—to get started.

Before making an autistic friend: Teaching inclusivity

Helping your child appreciate differences begins long before they make their first autistic friend.

Normalize differences. 

Children learn by watching you—so it’s important to model kind behavior. Talking about how people are unique normalizes those differences and makes being inclusive feel natural. 

Conversation starters: 

• Reinforce the idea that all humans have strengths and weaknesses.
• Celebrate differences you observe while reading books or watching shows together.

Teach your child about all forms of communication. 

Spoken language is just one way we communicate. We also use gestures, eye contact, facial expressions and physical actions to show our feelings. We ALL communicate slightly differently. 

Conversation starters: 

• Point out non-autistic family members and friends who communicate with their hands, wink often or give a lot of hugs.
• Ask your child how babies communicate to show what they need or want.

“It’s OK for your child to feel uncomfortable initially around people who seem different,” Dr. Liu says. “But as adults and guardians, we must highlight that differences are natural, and differences are important.”

“Fundamentally as humans, we have much more in common than we realize,” she adds. “We can find something in common with everyone, and our differences make our world more special and interesting.”

During: Helping your child befriend an autistic peer

If your child has a classmate with autism, help them understand the best ways to initiate friendship and what to expect. Dr. Liu recommends sharing this guidance with your non-autistic child:

Start the conversation.

Don’t shy away from an autistic classmate. Instead, approach them like anyone else.  

It’s okay to start a conversation with someone even if you’re not sure how they might respond. Try saying hello, asking what they like to do for fun, giving them a compliment, or inviting them to play. 

Check your expectations at the door.

Not all children with autism will respond to your efforts in ways you might expect but acknowledging someone and offering your friendship will go a long way in helping them feel welcome.

Don’t take things too personally.

People with autism communicate differently. They may be extra shy or excited. They might look away to feel more comfortable or get close to you to show their happiness. They might make extra body movements or sounds.

Try not to take these actions personally! They likely don’t understand how their actions make others feel.

Tell your friend how you feel. 

Children with autism care about their friends—but sometimes they might say things without filtering how they say it.

This may unintentionally hurt your feelings or make you uncomfortable. 

It’s OK for you to calmly and clearly tell them how you feel. 

You can say, “You probably didn’t do it on purpose, but you really upset me when you…” Your friend may not look at you when you talk to them, but they hear you. If your classmate continues to upset you, it’s okay to walk away, play somewhere else or talk to your teacher about it.

Look for what you have in common.

Even though you may only see the differences first, you probably have multiple things in common with your autistic classmate—you just need to discover them. 

Notice what they play with or ask them what they like to do. People with autism often know a lot about a specific topic and may be able to teach you something.

Consider playing next to—instead of with—your friend.

Some children with autism find it easier to play near their friends (parallel play). They’d rather not engage in games that require back-and-forth interactions. Parallel play allows autistic children to have boundaries and choose when and when not to talk. 

Examples of parallel play include:

• Building with blocks near each other
• Coloring side by side
• Playing with cars or action figures simultaneously

Learn to recognize signs of frustration.

If an autistic classmate seems irritated, they may feel frustrated, uncomfortable or misunderstood. 

When that happens, step back and say, “It’s OK.” Try to figure out why your friend might be frustrated. If you think something you did or said made them uncomfortable, let them know you won’t do that anymore.

“Every friendship your child has is unique and brings something to the table,” Dr Liu says. “The best thing your child can do is be kind and try to understand their autistic friend without expecting how they will respond.”

Ongoing: Nurturing friendships with autistic peers

An ongoing friendship between your child and an autistic classmate may include playdates, birthday parties, and other get-togethers outside of school. Dr. Liu suggests a few ways you can set your child and their friend up for success.

Prep your child.

Explain to your child that their friend may get overwhelmed and need space or time alone. Remind them that your family tries to make guests comfortable and doesn’t call out things guests do differently.

Plan ahead.

Planning helps ensure both kids have a positive experience. Before a playdate, find out what makes your child’s friend comfortable. 

• What snacks do they like? 
• What are their favorite toys, games, or activities?
• Are there activities or settings that can be overwhelming for them?

Don’t be afraid to ask questions.

If your child’s autistic friend is verbal, you can ask your guest about their preferences when they arrive. For nonverbal children, reach out to the parent beforehand. Ask them about their child’s tendencies and how often they may need a break from play.

“Parents of children with autism typically enjoy being able to talk about their child, including what makes them great and what they find challenging,” Dr. Liu says. “It’s always better to ask questions than assume you understand their child.”

No Green Light for Banks, Insurers in Commodity Derivatives, Says Sebi Chief

Mumbai, May 4 (BNP): The banking and insurance regulators in India are not in favour of allowing banks and insurance companies to participate in commodity derivatives markets, according to Securities and Exchange Board of India (SEBI) Chairman Tuhin Kanta Pandey.

Speaking at the IMC Capital Market Conference 2026 in Mumbai, Pandey said that both the Reserve Bank of India (RBI) and the Insurance Regulatory and Development Authority of India (IRDAI) have valid concerns regarding such exposure and are not inclined to permit it at this stage.

He noted that the regulators believe the risks associated with commodity derivatives may not align with the core objectives and risk frameworks of banks and insurance firms.

Pandey also mentioned that the pension regulator had previously examined the possibility of allowing pension funds to participate in commodity derivatives markets, though he did not disclose any final decision on the matter.

Overall, the comments highlight a cautious regulatory approach toward expanding participation in commodity derivatives beyond traditional market participants.

Mittal–Poonawalla Consortium Buys Stake in Rajasthan Royals in INR 15,660 Crore Deal!

New Delhi,May 4 (BNP): In a major development in the Indian Premier League, UK-based Indian billionaire Lakshmi Mittal and Adar Poonawalla have acquired a significant stake in Rajasthan Royals (RR) through a consortium deal valued at approximately ₹15,660 crore ($1.65 billion).

The two business leaders have partnered with existing principal owner Manoj Badale to form a new consortium that will not only control Rajasthan Royals but also its sister franchises—Paarl Royals in South Africa’s SA20 league and Barbados Royals in the Caribbean Premier League.

According to an official statement, post-transaction ownership will see the Mittal family holding around 75% stake in the franchise, while Adar Poonawalla will own approximately 18%. The remaining 7% will be retained by existing approved investors, including Manoj Badale, who will continue to play a key role, providing continuity and leveraging his extensive experience in cricket management.

The deal, announced after months of speculation over ownership changes, is subject to approvals from the Board of Control for Cricket in India and the Competition Commission of India.

Founded in 2008 as one of the original IPL franchises, Rajasthan Royals was initially acquired by Badale for $67 million and has since grown into a globally recognized cricket brand. The new investment underscores the rising valuation and international appeal of IPL teams.

The Mittal family already has a footprint in global sports, including investments in the NBA’s Boston Celtics and English football club Queens Park Rangers. Sources indicate that Aditya Mittal could emerge as a key figure representing the franchise going forward.

Expressing his enthusiasm, Lakshmi Mittal said he has a deep personal connection with both cricket and Rajasthan, adding that he looks forward to contributing to the team’s future success and engaging with its passionate fan base.

The transaction marks one of the largest deals in IPL history and is expected to further boost investor confidence in the league’s commercial potential.

Cyclone Alert? Low Pressure Likely in Bay of Bengal Mid-May; IMD Yet to Confirm

Bhubaneswar, May 4 (BNP): A potential weather system over the Bay of Bengal is drawing attention, with early model projections indicating the possible formation of a low-pressure area during the second week of May.

According to preliminary forecasts from the Global Forecast System, conditions may become conducive for the development of a cyclonic system around mid-May. Some projections even hint at a possible intensification, raising concerns of a cyclone threat.

However, the India Meteorological Department has not issued any official confirmation or warning regarding such a development so far. Meteorological experts caution that while environmental conditions appear favorable for cyclogenesis, it is too early to determine whether the system will intensify into a cyclone.

As of now, the situation remains under close watch, with further clarity expected in the coming days as more data becomes available. Authorities have advised