12, Jun 2023
Insights into Redox-Independent Cellular Stress Response
Researchers identify the regulatory pathway that governs a type of redox-independent stress response involving NRF2
Nuclear factor erythroid 2-related factor 2 (NRF2) is a master transcription factor with a role in regulating oxidative stress response. It can be activated via redox-dependent and independent pathways. Regulatory mechanisms of the redox-dependent pathway are known; however, the same cannot be said for the redox-independent pathway. Now, researchers from Juntendo University have unraveled the roles of phase-separated liquid droplets, p62 bodies, in redox-independent NRF2 activation and the significance of phosphorylation in this process.
Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA. Owing to their destructive nature, all cells have robust mechanisms in place to remove ROS and reduce oxidative stress. One such mechanism is the nuclear factor erythroid 2-related factor 2 (NRF2)-mediated stress response, where NRF2 is a master transcription factor that aids in reducing oxidative stress.
Much is known about the redox-dependent activation of NRF2 and its subsequent role in stress response. In this pathway, Kelch-like ECH-associated protein 1 (KEAP1) senses oxidative stress in the cell through oxidation of its specific cysteine residues. This oxidation causes conformational changes in KEAP1, which, in turn, loses the ability to suppress NRF2. As a result, NRF2 is stabilized and induces a series of genes encoding anti-oxidative proteins that reduce and remove oxidative stress caused by ROS.
NRF2 can also be activated in a redox-independent manner. This activation involves p62 protein, which undergoes liquid-liquid phase separation to form p62 bodies when it binds to ubiquitinated proteins upon defective proteostasis. However, the precise mechanism of NRF2 regulation through p62 bodies had hitherto remained largely unknown.
Now, researchers in Japan have found how p62 bodies control redox-independent NRF2 activation. They conducted a study that was conceived by Professor Masaaki Komatsu and Associate Professor Yoshinobu Ichimura from Juntendo University School of Medicine and Dr. Nobuo N. Noda from Hokkaido University. “We have reported in a previous study that phosphorylation of p62 inhibits the binding of KEAP1 to NRF2 competitively, thereby disabling the NRF2-repressive function of KEAP1. However, the regulatory mechanism and the physiological functions in vivo remain largely unclear. This is important as the accumulation of phosphorylated p62 has been found to cause many intractable diseases,” explains Prof. Komatsu when asked about the team’s motivation for pursuing the research. Their findings are all set to be published in The EMBO Journal.
Using advanced techniques like high-speed atomic force microscopy, fluorescence recovery after photobleaching, and fluorescence loss in photobleaching, the team conducted experiments that included those performed outside a living organism (in vitro) and those using cells and mice (in vivo) to thoroughly profile protein-protein interactions, cellular localization of specific components, and the effects of LLPS-induced p62 phosphorylation, during redox-independent NRF2 activation.
Summarizing the main findings of their study, Dr. Ichimura explains, “We found that ULK1, a protein kinase, translocates to p62 bodies and then phosphorylates p62 within the bodies. The resulting phosphorylated p62 bodies retain KEAP1 within them, which drives the activation of NRF2.”
KEAP1 usually cycles in and out of p62 bodies; however, phosphorylated p62 tightly binds to KEAP1, which causes KEAP1 to be retained and sequestered within the p62 body. This leads to activation of even more NRF2. The p62 bodies are degraded by autophagy, and this may contribute to shutdown of this pathway. The current study extends the scope of the antioxidative stress response and provides new insights into the role of phase separation in the process.
The importance of this redox-independent NRF2 activation was tested using phosphomimetic p62 knock-in mouse models where hyperactivation of NRF2 by extensive phosphorylation resulted in hyperkeratosis—a growth defect causing the outer layer of the stomach and esophageal lining to thicken, which in turn caused stunted growth due to malnutrition.
Prof. Komatsu is confident that his team has laid the foundation for future work to probe deeper into the mechanism and regulation of redox-independent stress responses. He concludes, “Whether redox-dependent or independent, NRF2 activation is an important biological defense system. Understanding its regulatory mechanisms is crucial as its persistent activation leads to inordinate defense responses, like excessive keratinization. Our study is the first scientific validation of the physiological significance for redox-independent NRF2 activation. In the case of redox-independent stress responses, activation of NRF2 is very likely regulated by phosphorylation, dephosphorylation, and autophagic degradation of p62 bodies. p62 bodies have been found to accumulate in affected cells in patients with liver disorders, neurodegenerative diseases, and cancers. Thus, research such as ours will be useful in elucidating the pathogenesis of and developing improved therapies for FA-, NRF2-, and autophagy-related diseases.”
- 0
- By Neel Achary
12, Jun 2023
Innovative Study Maps Grip Force as an Effective Stress Indicator for Safer Driving
12 June 2023
ARIEL, Israel — Researchers at Ariel University’s Department of Industrial Engineering & Management have made a breakthrough in stress measurement during driving tasks. The team has released a comprehensive study detailing the use of grip force on the steering wheel as a non-intrusive measure of driver stress, potentially paving the way for enhanced road safety systems.
The study’s aim was to map the various parameters affecting the relationship between grip force and stress during driving tasks. This innovative stress index, according to previous findings from the same team, requires a short time window of two to five seconds, making it an effective and user-friendly method.
“Reducing drivers’ stress can potentially increase road safety. State-of-the-art physiological stress indices are intrusive and limited by long time lags. Our approach of measuring grip force offers a transparent solution to the user and operates within a brief time window,” said Prof. Shraga Shoval one of the authors of the study.
The research involved two stressors: the driving mode and the distance from the vehicle to a crossing pedestrian. Thirty-nine participants performed driving tasks during either remote driving or simulated driving, with a pedestrian dummy unexpectedly crossing the road at two distances. The researchers then measured the grip force on the steering wheel and the skin conductance response.
The findings from the study will help in the development of car safety systems that incorporate continuous measurements of stress. They provide a comprehensive guide for researchers and professionals to use grip force for the purpose of measuring stress in a non-intrusive manner and with relatively short latencies.
The study was funded by the Israeli Innovation Authority through the Andromeda consortium.
12, Jun 2023
UK Nuclear Fusion company announces space rocket US Partnership
A British nuclear fusion company has joined forces with a leading American company to use AI to design a hyper-fast space rocket capable of reaching Saturn’s moons in just two years.
Oxfordshire based Pulsar Fusion have announced a partnership with Princeton Satellite Systems in a move which could drastically reduce the mission time to Saturn’s moon Titan.
The two leading British and American companies will use AI machine learning simulations to create a deep space rocket engine with a 500,000 mph potential – also making Mars reachable in just 30 days.
The move comes just days after Prime Minister Rishi Sunak signed a UK / US defence sharing deal in Washington.
A picture containing clothing, footwear, person, suit Description automatically generated.
Announcing the partnership Pulsar Fusion’s founder and CEO Richard Dinan said: “This is a hugely significant step for Pulsar. By pooling our own research and resources with those of Princeton Satellite Systems, Pulsar has gained access to behavioural data from the world record holding fusion reactor (PRFC-2) coupled with recent advancements in machine learning, this will supercharge the development of our nuclear fusion rocket systems.
“Fusion Propulsion is free from many of the vast infrastructure requirements presented in the development of terrestrial fusion energy for power stations on Earth.
“Space is the ideal place to do fusion in terms of it being a vacuum and the extremely cold temperatures.
“Unlike a fusion power station, fusion propulsion doesn’t require a giant steam turbine and fuels can be sourced externally rather than needing to be created on site.
“Humanity has a huge need for faster propulsion in our growing space economy and fusion offers 1000 x the power of conventional ion thrusters currently used in orbit. In short, if humans can achieve fusion for energy, then fusion propulsion in Space is inevitable.
“Our view is that fusion propulsion will be demonstrated in space decades before we can harness fusion for energy on Earth. “
The Science
The collaboration will see the two companies using AI machine learning to study data from the World record holding PFRC-2 reactor, in order to better understand the behaviour of plasma under electromagnetic heating and confinement, when configured as an aneutronic propulsion system.
In an exciting World first, the two companies will use data from plasma shots conducted at the Reversed Configuration reactor, the PFRC-2, which was developed in partnership with Princeton Plasma Physics Laboratory (PPL), and the most advanced machine learning technologies to analyse the behaviour of super-hot fusion plasma in a rocket engine configuration.
The research a transatlantic partnership that looks to uncover how a nuclear fusion Plasma will behave as it is exits a rocket engine emitting exhaust particles at hundreds of km per second.
Pulsar is developing simulations based on gas puffing data from the PFRC-2 to attempt to create predictive simulations of ion and electron behaviour in an FRC plasma.
Predictive simulations are needed for closed loop control systems, a key component of a future PFRC reactor. The PFRC-2 is located at the Princeton Plasma Physics Laboratory (PPPL) and supported in part by PSS.
Once developed the new technology could reduce the journey time to Mars to only 30 days and make Saturn’s moon Titan reachable within two years.
12, Jun 2023
‘Sea Hubs’ can boost economy, tourism and inspire creative professionals: Experts
Panaji, June 2023– Creating ‘Sea Hubs’, coastal co-working spaces along Goa’s shoreline not only has the potential to revitalise the state’s bouquet of tourism offerings, but can also provide a shot in the arm for the state’s economy and attract promising talent to the state.
At last week’s StartUp20 Engagement Group meeting, Goa’s IT Minister Rohan Khaunte had said that the state government was in the process of setting up 12 co-working spaces or ‘Sea Hubs’ along the shoreline which would be fashioned as creative hubs where young professionals could work in the lap of natural beauty.
According to V Padhmanabhan, Associate Professor, Organisational Behaviour and Human Resources at the Goa Institute of Management (GIM), setting up work hubs in a natural setting such as beaches could boost creativity, lessen stress and promote general health, while also boosting output and job satisfaction.
“The move can attract good talent, who can happily include leisure and relaxation into their everyday routines thanks to the existence of working spaces in these locations. For a better work-life balance, employees can take breaks or leave work early to engage in outdoor activities. People can remove or greatly minimise their need for long, stressful commutes by working in such settings,” Padmanabhan said.
Goa, Padmanabhan said, would greatly benefit from such co-working spaces which could potentially draw a variety of people, including national, international talent and experts from different fields.
“The presence of co-working zones in these areas can foster networking, teamwork and knowledge sharing,” he also said.
Young professionals, especially those in the creative and technology sectors in the recent past — during and after the pandemic — had made a beeline for Goa at a time when remote working was in vogue. Goa also witnessed a spurt of co-working spaces, where professionals, instead of hiring individual office spaces, could work in co-working spaces, thereby reducing establishment costs.
Creation of Sea Hubs, according to Aaron Fernandez, founder of Kilowott, a Goa-based technology company, would push the co-working space envelope further by creating a more empowering eco-system.
“This would elevate Goa’s status on the business map and also create an empowering ecosystem where young, emerging professionals can harness their creativity and talents while maintaining a harmonious work-life balance,” Fernandez said.
Fernandez also said that the Goa government’s plans to create a ‘Design Village’ and a ‘Creative Hub’ for artists, innovators and fin-tech, fashion-tech VFX and augmented reality and virtual reality professionals respectively would provide a nurturing environment to push the boundaries of creativity further.
Rohan Warty, secretary of the Goa Technology Association, says that the move to create Sea Hubs would also create more jobs in the state, while also aiding the advancement of talent and technology in Goa.
“We have seen co-working spaces on a small scale already existing informally in Goa post the pandemic. However, now with government support, it will provide a more structured opportunity for professionals across the globe. Increased presence of businesses will directly contribute to the economy. Hopefully, this initiative will attract big companies by showing them the scope for scalability in Goa,” he said.
‘Sea Hubs’ according to Nilesh Shah, president of the Travel and Tourism Association of Goa, would create a symbiotic relationship between work and leisure, which he says, holds the key to reviving tourism in the state, which is a vital pillar of the state’s economy.
“In the wake of Covid, a new phenomenon emerged: the work-cation, bringing together professionals from diverse backgrounds to work remotely. Hotels seized this opportunity, introducing the concept of workation. It presents a golden chance for nomadic employees and those craving a home office experience. With its breath-taking landscapes, Goa stands as the perfect destination for these intrepid explorers,” Shah said.
12, Jun 2023
Veet promises professional self-waxing results with Veet Professional® Wax strips
New Delhi, June 12, 2023: Veet®, the world leader in depilatory products, will provide consumers professional waxing like results with Veet Professional® wax strips. Brand ambassador Katrina Kaif in a new 360-degree campaign, ‘Professional Waxing made easy #VeetItToBelieveIt’, focuses on a superior, effective, and convenient hair removal solution that can help achieve professional waxing like results.
The Veet Professional® ready-to-use full-body wax strips offers smooth skin for up to 28 days* by removing the shortest* of hair. The new product pack comes with a unique QR code that directs the consumers to how-to-use videos, to educate and guide consumers who are trying to learn the right way to wax themselves at home.
Speaking about the campaign, Dilen Gandhi, Regional Marketing Director, South Asia – Health & Nutrition, Reckitt, said, “Effective and quick self-grooming solutions at home are a growing choice for consumers today and Veet is consistently working towards offering a superior and seamless experience, ensuring remarkable results within minutes. Our latest campaign ‘Professional Waxing made easy #VeetItToBelieveIt’ with brand ambassador Katrina Kaif takes self-waxing to the next level with professional waxing like results that can be achieved by consumers themselves. Veet is proud to be able to deliver this experience to millions across India.”
Anupama Ramaswamy, Chief Creative Officer Havas Worldwide India said, “Veet Professional® wax strips puts back the power of waxing in every woman’s hands. Not just the professional waxing like results, but the ease of using it is also bound to surprise everyone. Therefore, the TVC’s story demanded a surprise element. So, while the latest campaign highlights the professional waxing like results one can achieve with Veet Professional®, it also uses the brand ambassador Katrina Kaif in a surprising manner.”
The new ‘Professional Waxing made easy #VeetItToBelieveIt’ campaign engages young women of today who are constantly in search of professional yet convenient solutions for everyday tasks. The new TVC features a young woman who is getting ready for work and manages to wax in minutes using Veet Professional® wax strips which provides her the confidence and ease to wear what she wants and begin her day leaving her friends shocked. The TVC also features brand ambassador Katrina Kaif highlighting Veet Professional® wax strips as a quick, easy and reliable solution to get professional waxing like results by yourself, anywhere and anytime.
The Veet Professional® wax strips are available in retail stores across India and e-commerce websites at a starting price of INR 109 for Half Body Wax Strips (8 Strips).
TVC Link: https://www.youtube.com/watch?v=bcVVYOSqjh4
Director: Punit Malhotra
Production House: Little Lamb Films
Creative Agency: Havas Worldwide India
12, Jun 2023
Experience the best of Korean cuisine as Conrad Seoul flies to Conrad at the Garden City – Bengaluru
Celebrating the 50th anniversary of diplomatic ties between Korea and India, Conrad Bengaluru commemorates the occasion through a unique festival. Graced by The Embassy of the Republic of Korea and The Korea Tourism Organization, the curated vision celebrates the two nations through its rich culture, tradition and heritage.
Offering a tantalizing array of vibrant and exquisite flavours of Korea at Conrad Bengaluru, prepare to be swept away by a meticulously curated menu, masterfully crafted by renowned chefs from Conrad Seoul – Chef Lee and Chef Kim, along with the culinary genius Chef Indra, Conrad Bengaluru. Get ready to embark on a culinary journey showcasing the sizzle of Korean delicacies, making this feast an extraordinary event that truly must be bookmarked!
The exclusive food festival will showcase a tantalizing selection of traditional Korean dishes, crafted by the esteemed team of chefs of Conrad.
The menu will feature an array of iconic delicacies, Daeha Muchim– Prawn Salad with Pine Nut Sauce, Maekom Bulgogi Kimbap – Spicy Beef Rice Roll, Ganjang Lobsterjang – Soy marinated Lobster, Bulgogi Burger – Soy marinated Beef Slider with Ginseng Soy Sauce, Yanggogi Jorim – Braised Lamb with Soy Sauce, Chamchi-Hwae Dupbap – Mixed Rice with Tuna Sashimi, Vinegar Gochujang, Hwangjae Haemool Ramyun – Spicy Ramen with Lobster, Crab and Scallop and Yak Gwa – Deep-fried Korean Pastry with Traditional Syrup to name a few.
Paired alongside the national drink of Korea, the traditionally crafted beverage made from part rice and part vodka is best enjoyed when chilled and neat. Available in flavours such as strawberry, blueberry and classic, Soju is indeed a refreshing delight all the way from the 14th century.
“We are elated to be associating with the talented team from Conrad Seoul showcasing a display of vibrant and exquisite flavors of the Korean cuisine. Further embracing and fostering the relationship of two very diverse cultures and traditions, it brings us great pleasure to join hands with a nation such as Korea, denoting rich heritage and history similar to India. We seek to continue inspiring and create bonds of absolute friendship, and we are truly thrilled to bring the magic of Korea to Bengaluru”, said Mr. Srijan Vadhera, General Manager, Conrad Bengaluru.
“It gives us great pleasure to commemorate the ties of two very strong and diverse nations, India & Korea. Embracing the cultural partnership, we are delighted to celebrate the 50th anniversary of diplomatic ties between Korea and India at Conrad Bengaluru, a splendid display of culture, tradition and food, a collaborative yet significant association between Conrad Seoul & Conrad Bengaluru”, said His Excellency Chang Jae-bok, Ambassador of the Republic of Korea to India.
Chef Prasad Metrani, Director of Culinary, Conrad Bengaluru adds “This Korean Food Festival is a testament to our commitment to providing our guests with unforgettable dining experiences that highlight culinary diversity. We are confident that the combination of our talented chefs from Conrad Seoul and Conrad Bengaluru will create an extraordinary culinary event of relishing & delectable flavours.”
Chef Kim, Conrad Seoul adds, “I am thrilled to be part of the Korean Food Festival at Conrad Bengaluru. It is an incredible opportunity to showcase the rich flavors and cultural heritage of Korean cuisine to the discerning diners in Bengaluru. I look forward to creating a memorable culinary experience and sharing the authentic flavours and recipes of Korea”.
Get ready to embark on a culinary journey like no other with Conrad Bengaluru’s latest addition to their menu – authentic Korean cuisine! This scrumptious offering is guaranteed to leave food lovers in the city wanting more, while also being a game changer for enthusiasts of Korean culture.
Don’t miss out on this must-visit dining experience that’s sure to tantalize your taste buds and transport you to the heart of Korea.
Food promotion from: 16th June to 26th June 2023 at MIKUSU, Conrad Bengaluru | INR 3000 plus taxes onwards, for two (à la carte)
For Reservations: +9188844 00194 | +9180221 44352
12, Jun 2023
Eternal Glamour: Navrathan Jewellers Exquisite Diamond Jewellery
Diamonds are a symbol of luxury, timelessness, sophistication, strength and romance. Because of its exceptional qualities, it’s one of the most sought-after gems for jewellery today. For centuries, diamond jewellery has symbolised the strength of love and marriage, and it has become a classic choice for commitment. Modern women around the world now wear diamond jewellery to express themselves, and symbolise and commemorate significant moments including milestones in their lives. Despite popular belief, diamonds come in many different shapes, colours, and sizes, and there is a diamond out there for every woman and every budget. Navrathan Jewellers offers a stunning selection of diamond jewellery, providing a wide range of choices to suit every individual’s taste and style. Their collection showcases exquisite craftsmanship and intricate designs, making it easy for customers to find the perfect piece that reflects their unique personality and adds a touch of luxury to any ensemble.
Similarly, a diamond necklace is a must-have for every woman’s jewellery box. It’s a widely accepted fact that diamonds are a girl’s best friend. Navrathan Jewellers necklaces featuring diamonds come in an array of styles, from the classic diamond solitaire pendant to a unique and intricate necklace featuring multiple diamonds. Navrathan Jewellers diamond necklace, weighing approximately 68 grams with 18kt gold, is adorned with stunning diamonds weighing approximately 7.5 ct. With a price of approximately Rs. 11.25L, this diamond necklace is a testament to the exceptional craftsmanship and timeless beauty of Navrathan Jewellers designs.
Navrathan Jewellers diamond necklace is not only a stunning piece of jewellery but also a significant investment that will be treasured for a lifetime if properly cared for. It is an accessory that exudes sophistication and glamour, making a lasting impression no matter the occasion. Whether it’s a diamond bangle, a diamond necklace, or any other diamond jewellery piece, Navrathan Jewellers exquisite designs are sure to add a touch of elegance and allure to any look.
12, Jun 2023
Vaginal Prolapse: Symptoms, treatments and precautions
By Dr. Poornima Kinila, Consultant – Obstetrics & Gynecology and Infertility, Aster RV Hospital
The vagina is one of several organs located in the pelvic region. Muscles and other tissue hold these organs in place. These muscles work together to form a structure known as the pelvic floor. This support structure can begin to deteriorate over time. This can happen for a variety of causes, but the end effect is organ sagging. A prolapse occurs when your organs sag or droop from their natural position. When the top of the vagina weakens and collapses into your vaginal canal, this is known as vaginal prolapse. Prolapses can be minor or severe. An incomplete prolapse is a minor prolapse. When your organ has displaced significantly, you will experience a larger prolapse (full prolapse). Your organs may protrude from your vaginal entrance if you have a full prolapse. This is a really severe prolapse. Painful symptoms might result from vaginal prolapse. Surgery may not be necessary for mild to moderate vaginal prolapse. However, more severe cases may need surgical repair.
Your pelvis is made up of your uterus, vagina, rectum, bladder, and urethra. These organs are supported by your pelvic floor muscles, which resemble an upside-down umbrella. The umbrella supports your pelvic organs; however, it might collapse over time or due to other circumstances like vaginal delivery. There are various varieties of prolapse, each with a different name based on where the organ has slipped. The following are some examples of pelvic organ prolapse.
Vaginal prolapse is a rather frequent condition. During their lifespan, more than one-third of women or people assigned female at birth (AFAB) may experience some form of pelvic region prolapse. You’re more prone to have vaginal prolapse later in life, especially if you’ve had numerous vaginal births.
Symptoms
- Fullness, heaviness, or pain in the pelvic region. This sensation frequently worsens throughout the day or after standing, lifting, or coughing.
- Back ache in the lower back.
- Bulging in your uterus.
- You have the sensation that something is slipping out of your vagina.
- Pee dripping (urinary incontinence).
- Infections of the bladder occur on a regular basis.
- Pooping is difficult.
- Sexual intercourse problems.
- Tampon inserting issues.
Causes
A set of muscles and other tissue hold your vagina in place within your pelvis, forming a sort of support framework. This structure holds your pelvic organs in place. This structure may deteriorate with time. When this happens, your vagina may slip down and out of place, resulting in a prolapse. Among the most common causes of vaginal prolapse are:
- Childbirth: Vaginal delivery is more likely to result in prolapse than a C-section. If you’ve had several vaginal deliveries, had a lengthy labor, or delivered a large baby, your chance of prolapse may be increased (more than 9 pounds)
- Ageing: As you get older, your chances of prolapse increase.
- Excessive physical exercise or heavy lifting: Activity-related strain can also weaken your pelvic muscles and cause your organs to sag out of position.
- Factors of genetic or hereditary origin: Your pelvic support system may be naturally weaker.
- Prolapse can also be caused by activities or situations that put extra pressure on your abdominal area like:
- Failure to maintain a healthy body weight.
- Heavy lifting.
- Struggling to defecate.
- Having a persistent cough (common in people with asthma or respiratory problems
Treatment
Treatment for vaginal prolapse varies based on the severity of the prolapse. In certain circumstances, your healthcare physician may simply want to monitor it over time to ensure that it does not worsen.
Vaginal prolapses can be treated non- surgically or surgically. A few factors will be considered by the Obstetrics & Gynecology Hospital while developing a treatment plan, such as:
- Overall health, as well as any major medical issues.
- Age
- The seriousness of the prolapse.
- If you desire to have children later on.
- If you ever want to have penetrative sex.
12, Jun 2023
Ginni Filaments Ltd., the Leader sets a milestone with the first-ever 99.9% ‘paaniwipes’ for babies, manufactured in India
New Delhi, June 12, 2023: Ginni Filaments Ltd has launched ultra-pure water wipes, a first-of-its-kind in India, in the baby care segment. The pioneering product, containing 99.9% water, is the most pure and gentle wipe with minimal ingredients, developed understanding the unique properties of baby and infant skin.
Marketed and registered as ‘paaniwipes’ under the brand name ‘Adore Baby’, these high-water content wipes gently cleanse babies’ skin, providing a soothing and refreshing experience for babies including infants during clean-up sessions. These wipes are made up of incredibly soft, skin-friendly, and breathable nonwoven spunlace fabric, which protects babies’ silky-smooth skin from rashes and redness. Additionally, the wipes contain aloe vera, which helps to hydrate the skin and reduce inflammation.
With no added alcohol, parabens, chlorine, SLS, SLES, sulfates, or fragrances, these wet wipes are among the gentlest available in the market. Meticulously manufactured and adhering to the highest safety standards, the product has undergone dermatological testing and is FDA approved.
Commenting on the product, Yash Jaipuria, the Chief Executive of Ginni Filaments Ltd. said, “The gentle skin of babies is prone to irritation and inflammation from the chemicals used in normal wet wipes. Keeping their distinct needs in mind, we have carefully created this product that is high in water content and is loaded with the benefits of aloe vera. This is the first type of wet wipe manufactured in India that contains 99.9% water and is free from any kind of chemicals and artificial fragrance. Going forward, we plan to produce more such products for our other partners.”
Ginni Filaments has started producing this pioneering product for Rondeyvoo Eurasia, under the brand name ‘Adore Baby Wipes’. They are the purest wet wipes on the planet for the purest souls.
12, Jun 2023
Kotak Life signs MoU with Directorate General Resettlement (DGR) to Provide Employment Opportunities for Ex-Servicemen
New Delhi, 12th June 2023: Kotak Mahindra Life Insurance Company Limited (Kotak Life) today signed a Memorandum of Understanding (MOU) with the Directorate General Resettlement (DGR), an Inter Service organization functioning directly under the Department of Ex-Servicemen Welfare (Ministry of Defense) to offer employment opportunities to Ex-Servicemen of the Defence Services.
As per the MoU, Kotak Life will recruit Ex-Servicemen for various roles in the company and its affiliates by offering jobs across multiple distribution channels. This initiative aligns with Kotak Life’s recruitment strategy to foster diversity and tap into the immense potential of the disciplined, hardworking, and resilient individuals who have dedicated their lives to serving and protecting our nation.
Major General Sharad Kapur, YSM, SM, Director General Resettlement said, “Our partnership with Kotak Life increases the visibility of our ex-servicemen in the corporate sector and helps in achieving the objectives of providing skilled manpower and giving them a dignified second career.”
Mahesh Balasubramanian, Managing Director, Kotak Mahindra Life Insurance Company said, “Through this initiative, it is our sincere endeavour to acknowledge the service of our ex-servicemen bravehearts who have served and protected our nation. The partnership aims to leverage the skills and dedication of our armed force personnel by offering to continue serving the nation through life insurance coverage.
The collaboration will enable retired Ex-Servicemen to maintain a work-life balance while staying close to their families in their hometowns.”
